Direct transcriptional repression by pRB and its reversal by specific cyclins.

It was recently shown that the E2F-pRB complex is a negative transcriptional regulator. However, it was not determined whether the whole complex or pRB alone is required for repression. Here we show that pRB and the related protein p107 are capable of direct transcriptional repression independent of...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Bremner, R, Cohen, B L, Sopta, M, Hamel, P A, Ingles, C J, Gallie, B L, Phillips, R A
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1995
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230558/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7760821/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.6.3256
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