Direct transcriptional repression by pRB and its reversal by specific cyclins.

It was recently shown that the E2F-pRB complex is a negative transcriptional regulator. However, it was not determined whether the whole complex or pRB alone is required for repression. Here we show that pRB and the related protein p107 are capable of direct transcriptional repression independent of...

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Bibliografiska uppgifter
Huvudupphovsmän: Bremner, R, Cohen, B L, Sopta, M, Hamel, P A, Ingles, C J, Gallie, B L, Phillips, R A
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1995
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC230558/
https://ncbi.nlm.nih.gov/pubmed/7760821
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