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Identification of human and mouse p19, a novel CDK4 and CDK6 inhibitor with homology to p16ink4.

The cell cycle in mammalian cells is regulated by a series of cyclins and cyclin-dependent kinases (CDKs). The G1/S checkpoint is mainly dictated by the kinase activities of the cyclin D-CDK4 and/or cyclin D-CDK6 complex and the cyclin E-CDK2 complex. These G1 kinases can in turn be regulated by cel...

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Main Authors: Chan, F K, Zhang, J, Cheng, L, Shapiro, D N, Winoto, A
格式: Artigo
語言:Inglês
出版: 1995
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC230498/
https://ncbi.nlm.nih.gov/pubmed/7739548
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