Phosphotyrosine-dependent interaction of SHC and insulin receptor substrate 1 with the NPEY motif of the insulin receptor via a novel non-SH2 domain.
The SHC proteins have been implicated in insulin receptor (IR) signaling. In this study, we used the sensitive two-hybrid assay of protein-protein interaction to demonstrate that SHC interacts directly with the IR. The interaction is mediated by SHC amino acids 1 to 238 and is therefore independent...
Сохранить в:
| Опубликовано в:: | Mol Cell Biol |
|---|---|
| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Taylor & Francis
1995
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230480/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7537849/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.5.2500 |
| Метки: |
Нет меток, Требуется 1-ая метка записи!
|