Multiple independent inputs are required for activation of the p70 S6 kinase.

Previous studies have shown that the noncatalytic carboxy-terminal tail of the p70 S6 kinase (amino acids 422 to 525) contains an autoinhibitory pseudosubstrate domain that is phosphorylated in situ during activation and in vitro by mitogen-activated protein kinases. The present study shows that a r...

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Hlavní autoři: Weng, Q P, Andrabi, K, Kozlowski, M T, Grove, J R, Avruch, J
Médium: Artigo
Jazyk:Inglês
Vydáno: 1995
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC230461/
https://ncbi.nlm.nih.gov/pubmed/7739516
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