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Insulin activates a 70-kDa S6 kinase through serine/threonine-specific phosphorylation of the enzyme polypeptide.

The dominant insulin-stimulated ribosomal protein S6 kinase activity was purified to near homogeneity from insulin-treated 32P-labeled rat H4 hepatoma cells and found to copurify with a 70-kDa 32P-labeled polypeptide. The dominant S6 kinase purified from livers of cycloheximide-treated rats is also...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Price, D J, Gunsalus, J R, Avruch, J
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54868/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2122450/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.20.7944
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