The nonamer UUAUUUAUU is the key AU-rich sequence motif that mediates mRNA degradation.
Labile mRNAs that encode cytokine and immediate-early gene products often contain AU-rich sequences within their 3' untranslated region (UTR). These AU-rich sequences appear to be key determinants of the short half-lives of these mRNAs, although the sequence features of these elements and the mechan...
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| Опубликовано в:: | Mol Cell Biol |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Taylor & Francis
1995
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230450/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7891716/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.4.2219 |
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