Disruption of transforming growth factor beta signaling by a mutation that prevents transphosphorylation within the receptor complex.

T beta R-II (transforming growth factor beta [TGF-beta] type II receptor) is a transmembrane serine/threonine kinase that acts as the primary TGF-beta receptor. Ligand binding to T beta R-II leads to the recruitment and phosphorylation of T beta R-I, a distantly related transmembrane kinase that act...

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Sonraí Bibleagrafaíochta
Main Authors: Cárcamo, J, Zentella, A, Massagué, J
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1995
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC230381/
https://ncbi.nlm.nih.gov/pubmed/7862150
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