Disruption of transforming growth factor beta signaling by a mutation that prevents transphosphorylation within the receptor complex.
T beta R-II (transforming growth factor beta [TGF-beta] type II receptor) is a transmembrane serine/threonine kinase that acts as the primary TGF-beta receptor. Ligand binding to T beta R-II leads to the recruitment and phosphorylation of T beta R-I, a distantly related transmembrane kinase that act...
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| Udgivet i: | Mol Cell Biol |
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| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Taylor & Francis
1995
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230381/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7862150/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.3.1573 |
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