Sequence and structural requirements for high-affinity DNA binding by the WT1 gene product.
The Wilms' tumor suppressor gene, WT1, encodes a zinc finger polypeptide which plays a key role regulating cell growth and differentiation in the urogenital system. Using the whole-genome PCR approach, we searched murine genomic DNA for high-affinity WT1 binding sites and identified a 10-bp motif 5'...
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| Vydáno v: | Mol Cell Biol |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Taylor & Francis
1995
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230373/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7862142/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.3.1489 |
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