Mutations in the SHR5 gene of Saccharomyces cerevisiae suppress Ras function and block membrane attachment and palmitoylation of Ras proteins.

We have identified a gene, SHR5, in a screen for extragenic suppressors of the hyperactive RAS2Val-19 mutation in the budding yeast Saccharomyces cerevisiae. SHR5 was cloned, sequenced, and found to encode a 23-kDa protein not significantly homologous to other proteins in the current data bases. Gen...

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Detaylı Bibliyografya

Yayımlandı:	Mol Cell Biol
Asıl Yazarlar:	Jung, V, Chen, L, Hofmann, S L, Wigler, M, Powers, S
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	Taylor & Francis 1995
Konular:	Research Article
Online Erişim:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230357/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7532279/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.3.1333
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