Propagation of prion strains through specific conformers of the prion protein.

Two prion strains with identical incubation periods in mice exhibited distinct incubation periods and different neuropathological profiles upon serial transmission to transgenic mice expressing chimeric Syrian hamster/mouse (MH2M) prion protein (PrP) genes [Tg(MH2M) mice] and subsequent transmission...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Scott, M R, Groth, D, Tatzelt, J, Torchia, M, Tremblay, P, DeArmond, S J, Prusiner, S B
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230204/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9371560/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.12.9032-9044.1997
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