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Alendronate decreases orthotopic PC-3 prostate tumor growth and metastasis to prostate-draining lymph nodes in nude mice

BACKGROUND: Metastatic prostate cancer is associated with a high morbidity and mortality but the spreading mechanisms are still poorly understood. The aminobisphosphonate alendronate, used to reduce bone loss, has also been shown to inhibit the invasion and migration of prostate cancer cells in vitr...

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Detalhes bibliográficos
Main Authors: Tuomela, Johanna M, Valta, Maija P, Väänänen, Kalervo, Härkönen, Pirkko L
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2294135/
https://ncbi.nlm.nih.gov/pubmed/18371232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-8-81
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