Dengue 2 PDK-53 Virus as a Chimeric Carrier for Tetravalent Dengue Vaccine Development

Attenuation markers of the candidate dengue 2 (D2) PDK-53 vaccine virus are encoded by mutations that reside outside of the structural gene region of the genome. We engineered nine dengue virus chimeras containing the premembrane (prM) and envelope (E) genes of wild-type D1 16007, D3 16562, or D4 10...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	J Virol
Hauptverfasser:	Huang, Claire Y.-H., Butrapet, Siritorn, Tsuchiya, Kiyotaka R., Bhamarapravati, Natth, Gubler, Duane J., Kinney, Richard M.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2003
Schlagworte:	Vaccines and Antiviral Agents
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC229366/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14557629/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.21.11436-11447.2003
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