Chimeric Yellow Fever/Dengue Virus as a Candidate Dengue Vaccine: Quantitation of the Dengue Virus-Specific CD8 T-Cell Response

We have constructed a chimeric yellow fever/dengue (YF/DEN) virus, which expresses the premembrane (prM) and envelope (E) genes from DEN type 2 (DEN-2) virus in a YF virus (YFV-17D) genetic background. Immunization of BALB/c mice with this chimeric virus induced a CD8 T-cell response specific for th...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	van der Most, Robbert G., Murali-Krishna, Kaja, Ahmed, Rafi, Strauss, James H.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Pathogenesis and Immunity
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112342/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10933719/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.17.8094-8101.2000
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