Dengue 2 PDK-53 Virus as a Chimeric Carrier for Tetravalent Dengue Vaccine Development

Attenuation markers of the candidate dengue 2 (D2) PDK-53 vaccine virus are encoded by mutations that reside outside of the structural gene region of the genome. We engineered nine dengue virus chimeras containing the premembrane (prM) and envelope (E) genes of wild-type D1 16007, D3 16562, or D4 10...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Huang, Claire Y.-H., Butrapet, Siritorn, Tsuchiya, Kiyotaka R., Bhamarapravati, Natth, Gubler, Duane J., Kinney, Richard M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2003
Assuntos:	Vaccines and Antiviral Agents
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC229366/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14557629/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.21.11436-11447.2003
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