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β-Catenin Interacts with MyoD and Regulates Its Transcription Activity

Wnt regulation of muscle development is thought to be mediated by the β-catenin-TCF/LEF-dependent canonical pathway. Here we demonstrate that β-catenin, not TCF/LEF, is required for muscle differentiation. We showed that β-catenin interacts directly with MyoD, a basic helix-loop-helix transcription...

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Detalhes bibliográficos
Main Authors: Kim, Chang-Hoon, Neiswender, Hannah, Baik, Eun Joo, Xiong, Wen C., Mei, Lin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2293083/
https://ncbi.nlm.nih.gov/pubmed/18316399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01682-07
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