β-Catenin is essential for differentiation of primary myoblasts via cooperation with MyoD and α-catenin

Canonical Wnts promote myoblast differentiation; however, the role of β-catenin in adult myogenesis has been contentious, and its mechanism(s) unclear. Using CRISPR-generated β-catenin-null primary adult mouse myoblasts, we found that β-catenin was essential for morphological differentiation and tim...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Development
Hauptverfasser: Cui, Shuang, Li, Liang, Yu, Ruth T., Downes, Michael, Evans, Ronald M., Hulin, Julie-Ann, Makarenkova, Helen P., Meech, Robyn
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists Ltd 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6451316/
https://ncbi.nlm.nih.gov/pubmed/30683662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.167080
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge