β-Catenin is essential for differentiation of primary myoblasts via cooperation with MyoD and α-catenin

Canonical Wnts promote myoblast differentiation; however, the role of β-catenin in adult myogenesis has been contentious, and its mechanism(s) unclear. Using CRISPR-generated β-catenin-null primary adult mouse myoblasts, we found that β-catenin was essential for morphological differentiation and tim...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Cui, Shuang, Li, Liang, Yu, Ruth T., Downes, Michael, Evans, Ronald M., Hulin, Julie-Ann, Makarenkova, Helen P., Meech, Robyn
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6451316/
https://ncbi.nlm.nih.gov/pubmed/30683662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.167080
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