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β-Catenin is essential for differentiation of primary myoblasts via cooperation with MyoD and α-catenin
Canonical Wnts promote myoblast differentiation; however, the role of β-catenin in adult myogenesis has been contentious, and its mechanism(s) unclear. Using CRISPR-generated β-catenin-null primary adult mouse myoblasts, we found that β-catenin was essential for morphological differentiation and tim...
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| Veröffentlicht in: | Development |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Company of Biologists Ltd
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6451316/ https://ncbi.nlm.nih.gov/pubmed/30683662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.167080 |
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