High-Capacity Adenovirus Vector-Mediated Anti-Glioma Gene Therapy in the Presence of Systemic Antiadenovirus Immunity

Gene therapy is proposed as a novel therapeutic strategy for treating glioblastoma multiforme (GBM), a devastating brain cancer. In the clinic, antivector immune responses pose formidable challenges. Herein we demonstrate that high-capacity adenovirus vectors (HC-Ads) carrying the conditional cytoto...

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Hlavní autoři: King, Gwendalyn D., Muhammad, A. K. M. Ghulam, Xiong, Weidong, Kroeger, Kurt M., Puntel, Mariana, Larocque, Daniel, Palmer, Donna, Ng, Philip, Lowenstein, Pedro R., Castro, Maria G.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2008
Témata:
Gene Delivery
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2293067/
https://ncbi.nlm.nih.gov/pubmed/18287240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00232-08
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