The E6 Oncoproteins from Human Betapapillomaviruses Differentially Activate Telomerase through an E6AP-Dependent Mechanism and Prolong the Lifespan of Primary Keratinocytes

Human papillomaviruses (HPVs) belonging to the Betapapillomavirus genus have recently been implicated in squamous cell carcinomas of the skin, though the mechanisms by which they initiate carcinogenesis are unclear. We show that human foreskin keratinocytes (HFKs) expressing several betapapillomavir...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Bedard, Kristin M., Underbrink, Michael P., Howie, Heather L., Galloway, Denise A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology (ASM) 2008
Pynciau:
Transformation and Oncogenesis
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2292992/
https://ncbi.nlm.nih.gov/pubmed/18256157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01818-07
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