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SIRT1, an Antiinflammatory and Antiaging Protein, Is Decreased in Lungs of Patients with Chronic Obstructive Pulmonary Disease

Rationale: Abnormal inflammation and accelerated decline in lung function occur in patients with chronic obstructive pulmonary disease (COPD). Human sirtuin (SIRT1), an antiaging and antiinflammatory protein, is a metabolic NAD(+)-dependent protein/histone deacetylase that regulates proinflammatory...

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Main Authors: Rajendrasozhan, Saravanan, Yang, Se-Ran, Kinnula, Vuokko L., Rahman, Irfan
格式: Artigo
語言:Inglês
出版: American Thoracic Society 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2292827/
https://ncbi.nlm.nih.gov/pubmed/18174544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200708-1269OC
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