Assembly and Channel Opening in a Bacterial Drug Efflux Machine

Drugs and certain proteins are transported across the membranes of Gram-negative bacteria by energy-activated pumps. The outer membrane component of these pumps is a channel that opens from a sealed resting state during the transport process. We describe two crystal structures of the Escherichia col...

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Détails bibliographiques
Auteurs principaux: Bavro, Vassiliy N., Pietras, Zbigniew, Furnham, Nicholas, Pérez-Cano, Laura, Fernández-Recio, Juan, Pei, Xue Yuan, Misra, Rajeev, Luisi, Ben
Format: Artigo
Langue:Inglês
Publié: Cell Press 2008
Sujets:
Short Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2292822/
https://ncbi.nlm.nih.gov/pubmed/18406332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.02.015
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