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New Active Drugs against Liver Stages of Plasmodium Predicted by Molecular Topology
We conducted a quantitative structure-activity relationship (QSAR) study based on a database of 127 compounds previously tested against the liver stage of Plasmodium yoelii in order to develop a model capable of predicting the in vitro antimalarial activities of new compounds. Topological indices we...
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Main Authors: | , , , , , , , , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
American Society for Microbiology (ASM)
2008
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2292524/ https://ncbi.nlm.nih.gov/pubmed/18212104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01043-07 |
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