Prediction of Quinolone Activity against Mycobacterium avium by Molecular Topology and Virtual Computational Screening

We conducted a quantitative structure-activity relationship study using a database of 158 quinolones previously tested against Mycobacterium avium-M. intracellulare complex in order to develop a model capable of predicting the activity of new quinolones against the M. avium-M. intracellulare complex...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Gozalbes, Rafael, Brun-Pascaud, Monique, García-Domenech, Ramon, Gálvez, Jorge, Girard, Pierre-Marie, Doucet, Jean-Pierre, Derouin, Francis
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Mechanisms of Action: Physiological Effects
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90149/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10991858/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.10.2764-2770.2000
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