A Plant-Derived Morphinan as a Novel Lead Compound Active against Malaria Liver Stages

BACKGROUND: The global spread of multidrug–resistant malaria parasites has led to an urgent need for new chemotherapeutic agents. Drug discovery is primarily directed to the asexual blood stages, and few drugs that are effective against the obligatory liver stages, from which the pathogenic blood in...

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Detalhes bibliográficos
Main Authors: Carraz, Maëlle, Jossang, Akino, Franetich, Jean-François, Siau, Anthony, Ciceron, Liliane, Hannoun, Laurent, Sauerwein, Robert, Frappier, François, Rasoanaivo, Philippe, Snounou, Georges, Mazier, Dominique
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2006
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1716192/
https://ncbi.nlm.nih.gov/pubmed/17194195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0030513
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