New Active Drugs against Liver Stages of Plasmodium Predicted by Molecular Topology

We conducted a quantitative structure-activity relationship (QSAR) study based on a database of 127 compounds previously tested against the liver stage of Plasmodium yoelii in order to develop a model capable of predicting the in vitro antimalarial activities of new compounds. Topological indices we...

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Detalhes bibliográficos
Main Authors: Mahmoudi, Nassira, Garcia-Domenech, Ramon, Galvez, Jorge, Farhati, Khemais, Franetich, Jean-François, Sauerwein, Robert, Hannoun, Laurent, Derouin, Francis, Danis, Martin, Mazier, Dominique
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Susceptibility
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2292524/
https://ncbi.nlm.nih.gov/pubmed/18212104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01043-07
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