Proteolytic cleavage of Livin (ML-IAP) in apoptotic melanoma cells potentially mediated by a non-canonical caspase

BACKGROUND: Several inhibitor of apoptosis proteins (IAPs) are cleaved during apoptosis. Studies of the melanoma-associated IAP (ML-IAP) Livin, using recombinant molecules, have implicated both caspases 3/7 and the serine protease Omi/HtrA2 in its proteolytic cleavage. OBJECTIVE: To characterize the...

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Huvudupphovsmän: Yan, Hui, Brouha, Brook, Liu, Tong, Raj, Deepak, Biddle, Diana, Lee, Ray, Grossman, Douglas
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2006
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2292408/
https://ncbi.nlm.nih.gov/pubmed/16806840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jdermsci.2006.05.007
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