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P52-S Characterization of the Number of CAG repeats in the Huntingtin Gene of a Huntington Disease (HD) Mouse Strain by Fragment Analysis and DNA Sequencing
Mutations in the human Huntingtin gene cause the neurological disorder Huntington’s disease (HD). Specifically, the expansion of a trinucleotide repeat (CAG) in excess of 39 leads to a disease state in individuals. Therefore, determining the number of repeats in subjects is important, since the numb...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Association of Biomolecular Resource Facilities
2007
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2291987/ |
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