P52-S Characterization of the Number of CAG repeats in the Huntingtin Gene of a Huntington Disease (HD) Mouse Strain by Fragment Analysis and DNA Sequencing

Mutations in the human Huntingtin gene cause the neurological disorder Huntington’s disease (HD). Specifically, the expansion of a trinucleotide repeat (CAG) in excess of 39 leads to a disease state in individuals. Therefore, determining the number of repeats in subjects is important, since the numb...

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Bibliographic Details
Main Authors: Zianni, M. R., Glass, O., Ma, T., Hoyt, K.
Format: Artigo
Language:Inglês
Published: The Association of Biomolecular Resource Facilities 2007
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Poster Abstracts: DNA Sequencing
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2291987/
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