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Purification of ribonucleotide reductase subunits Y1, Y2, Y3, and Y4 from yeast: Y4 plays a key role in diiron cluster assembly

Ribonucleotide reductases (RNRs) catalyze the conversion of nucleotides to deoxynucleotides. Class I RNRs are composed of two types of subunits: RNR1 contains the active site for reduction and the binding sites for the nucleotide allosteric effectors. RNR2 contains the diiron-tyrosyl radical (Y⋅) co...

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Détails bibliographiques
Auteurs principaux: Nguyen, Hiep-Hoa T., Ge, Jie, Perlstein, Deborah L., Stubbe, JoAnne
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences 1999
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC22918/
https://ncbi.nlm.nih.gov/pubmed/10535923
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