PDL1 Is Required for Peripheral Transplantation Tolerance and Protection from Chronic Allograft Rejection

The PD-1:PDL pathway plays an important role in regulating alloimmune responses but its role in transplantation tolerance is unknown. We investigated the role of PD-1:PDL costimulatory pathway in peripheral and a well established model of central transplantation tolerance. Early as well as delayed b...

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Detalhes bibliográficos
Main Authors: Tanaka, Katsunori, Albin, Monica J., Yuan, Xueli, Yamaura, Kazuhiro, Habicht, Antje, Murayama, Takaya, Grimm, Martin, Waaga, Ana Maria, Ueno, Takuya, Padera, Robert F., Yagita, Hideo, Azuma, Miyuki, Shin, Tahiro, Blazar, Bruce R., Rothstein, David M., Sayegh, Mohamed H., Najafian, Nader
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2291549/
https://ncbi.nlm.nih.gov/pubmed/17911605
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