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Population pharmacokinetics and exploratory pharmacodynamics of ifosfamide according to continuous or short infusion schedules: an n = 1 randomized study
AIMS: To model the pharmacokinetics and pharmacodynamics of ifosfamide and its key metabolites. The pharmacodynamic parameters included were renal toxicity and myelosuppression measured using urinary β(2)-microglobulin (BMG) and absolute neutrophil count (ANC), respectively. METHODS: Seventeen patie...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Blackwell Science Inc
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2291389/ https://ncbi.nlm.nih.gov/pubmed/18294323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2007.03095.x |
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