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Exosites in the substrate specificity of blood coagulation reactions

The specificity of blood coagulation proteinases for substrate, inhibitor, and effector recognition is mediated by exosites on the surfaces of the catalytic domains, physically separated from the catalytic site. Some thrombin ligands bind specifically to either exosite I or II, while others engage b...

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Autors principals: BOCK, P. E., PANIZZI, P., VERHAMME, I. M. A.
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2291348/
https://ncbi.nlm.nih.gov/pubmed/17635714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1538-7836.2007.02496.x
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