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Exosites in the substrate specificity of blood coagulation reactions
The specificity of blood coagulation proteinases for substrate, inhibitor, and effector recognition is mediated by exosites on the surfaces of the catalytic domains, physically separated from the catalytic site. Some thrombin ligands bind specifically to either exosite I or II, while others engage b...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2291348/ https://ncbi.nlm.nih.gov/pubmed/17635714 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1538-7836.2007.02496.x |
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