Interindividual variability in the concentration–effect relationship of antilymphocyte globulins—a possible influence of FcγRIIIa genetic polymorphism

AIMS: Polyclonal antilymphocyte globulins (ALGs) are currently used in transplantation, but the sources of interindividual variability of their effect are poorly understood. No pharmacokinetic–pharmacodynamic (PK–PD) study of ALG is available. Moreover, the genetic polymorphism of FcγRIIIa, a recept...

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Bibliografiska uppgifter
Huvudupphovsmän: Ternant, David, Büchler, Matthias, Bénéton, Maud, Alván, Gunnar, Ohresser, Marc, Touchard, Guy, de Ligny, Bruno Hurault, Toupance, Olivier, Watier, Hervé, Lebranchu, Yvon, Paintaud, Gilles
Materialtyp: Artigo
Språk:Inglês
Publicerad: Blackwell Science Inc 2008
Ämnen:
Pharmacogenetics
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2291273/
https://ncbi.nlm.nih.gov/pubmed/17610526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2007.02967.x
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