Interindividual variability in the concentration–effect relationship of antilymphocyte globulins—a possible influence of FcγRIIIa genetic polymorphism

AIMS: Polyclonal antilymphocyte globulins (ALGs) are currently used in transplantation, but the sources of interindividual variability of their effect are poorly understood. No pharmacokinetic–pharmacodynamic (PK–PD) study of ALG is available. Moreover, the genetic polymorphism of FcγRIIIa, a recept...

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Détails bibliographiques
Auteurs principaux: Ternant, David, Büchler, Matthias, Bénéton, Maud, Alván, Gunnar, Ohresser, Marc, Touchard, Guy, de Ligny, Bruno Hurault, Toupance, Olivier, Watier, Hervé, Lebranchu, Yvon, Paintaud, Gilles
Format: Artigo
Langue:Inglês
Publié: Blackwell Science Inc 2008
Sujets:
Pharmacogenetics
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2291273/
https://ncbi.nlm.nih.gov/pubmed/17610526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2007.02967.x
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