The effect of age, gender, and body mass index on the pharmacokinetics and pharmacodynamics of vildagliptin in healthy volunteers

AIMS: To evaluate the effect of age, gender, and body mass index (BMI) on the pharmacokinetics and pharmacodynamics of vildagliptin. METHODS: Forty healthy subjects received a single oral dose of 100 mg vildagliptin to assess the effects of age, gender, and BMI on the pharmacokinetics and pharmacody...

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Bibliographic Details
Main Authors: He, Yan-Ling, Sabo, Ron, Campestrini, Joelle, Wang, Yibin, Riviere, Gilles-Jacques, Nielsen, Jace C, Rosenberg, Mitchell, Ligueros-Saylan, Monica, Howard, Dan, Dole, William P
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2008
Subjects:
Pharmacokinetics and Pharmacodynamics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2291246/
https://ncbi.nlm.nih.gov/pubmed/17961192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2007.03031.x
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