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Pharmacokinetic–pharmacodynamic model for perindoprilat regional haemodynamic effects in healthy volunteers and in congestive heart failure patients

AIMS: We compared the relationships between the plasma concentrations (C) of perindoprilat, active metabolite of the angiotensin I-converting enzyme inhibitor (ACEI) perindopril, and the effects (E) induced on plasma converting enzyme activity (PCEA) and brachial vascular resistance (BVR) in healthy...

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Bibliografiske detaljer
Main Authors: Bellissant, Eric, Giudicelli, Jean-François
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014509/
https://ncbi.nlm.nih.gov/pubmed/11453887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.0306-5251.2001.01410.x
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