Pharmacokinetics and pharmacodynamics of midazolam administered as a concentrated intranasal spray. A study in healthy volunteers

AIMS: To investigate the pharmacokinetic and pharmacodynamic profile of midazolam administered as a concentrated intranasal spray, compared with intravenous midazolam, in healthy adult subjects. METHODS: Subjects were administered single doses of 5 mg midazolam intranasally and intravenously in a cr...

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Hlavní autoři: Knoester, P D, Jonker, D M, van der Hoeven, R T M, Vermeij, T A C, Edelbroek, P M, Brekelmans, G J, de Haan, G J
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2002
Témata:
Pharmacokinetics/Pharmacodynamics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1874346/
https://ncbi.nlm.nih.gov/pubmed/11994056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2002.01588.x
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