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Population pharmacokinetics of gemcitabine and its metabolite in patients with cancer: effect of oxaliplatin and infusion rate
AIMS: To characterize the population pharmacokinetics of gemcitabine and its metabolite (dFdU) in patients with cancer and identify factors that are influential in gemcitabine dose regimen design. METHODS: Gemcitabine and dFdU plasma concentration–time and clinical data from 94 patients with cancer...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
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Blackwell Science Inc
2008
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2291243/ https://ncbi.nlm.nih.gov/pubmed/17961191 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2007.03040.x |
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