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Population pharmacokinetics and dosing regimen design of milrinone in preterm infants

AIMS: To define the pharmacokinetics of milrinone in very preterm infants and determine an optimal dose regimen to prevent low systemic blood flow in the first 12 h after birth. METHODS: A prospective open‐labelled, dose‐escalation pharmacokinetic study was undertaken in two stages. In stage one, in...

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Detalhes bibliográficos
Main Authors: Paradisis, Mary, Jiang, Xuemin, McLachlan, Andrew J, Evans, Nick, Kluckow, Martin, Osborn, David
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2675339/
https://ncbi.nlm.nih.gov/pubmed/16690639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/adc.2005.092817
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