Concerted regulation of focal adhesion dynamics by galectin-3 and tyrosine-phosphorylated caveolin-1

Both tyrosine-phosphorylated caveolin-1 (pY14Cav1) and GlcNAc-transferase V (Mgat5) are linked with focal adhesions (FAs); however, their function in this context is unknown. Here, we show that galectin-3 binding to Mgat5-modified N-glycans functions together with pY14Cav1 to stabilize focal adhesio...

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Bibliografiske detaljer
Main Authors: Goetz, Jacky G., Joshi, Bharat, Lajoie, Patrick, Strugnell, Scott S., Scudamore, Trevor, Kojic, Liliana D., Nabi, Ivan R.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2008
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2290850/
https://ncbi.nlm.nih.gov/pubmed/18347068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200709019
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