Orchestration of the S-phase and DNA damage checkpoint pathways by replication forks from early origins

The S-phase checkpoint activated at replication forks coordinates DNA replication when forks stall because of DNA damage or low deoxyribonucleotide triphosphate pools. We explore the involvement of replication forks in coordinating the S-phase checkpoint using dun1Δ cells that have a defect in the n...

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Main Authors: Caldwell, Julie M., Chen, Yinhuai, Schollaert, Kaila L., Theis, James F., Babcock, George F., Newlon, Carol S., Sanchez, Yolanda
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2008
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2290838/
https://ncbi.nlm.nih.gov/pubmed/18347065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200706009
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