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Orchestration of the S-phase and DNA damage checkpoint pathways by replication forks from early origins

The S-phase checkpoint activated at replication forks coordinates DNA replication when forks stall because of DNA damage or low deoxyribonucleotide triphosphate pools. We explore the involvement of replication forks in coordinating the S-phase checkpoint using dun1Δ cells that have a defect in the n...

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Autori principali: Caldwell, Julie M., Chen, Yinhuai, Schollaert, Kaila L., Theis, James F., Babcock, George F., Newlon, Carol S., Sanchez, Yolanda
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2290838/
https://ncbi.nlm.nih.gov/pubmed/18347065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200706009
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