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Evolution of polyketide synthases in bacteria

The emergence of resistant strains of human pathogens to current antibiotics, along with the demonstrated ability of polyketides as antimicrobial agents, provides strong motivation for understanding how polyketide antibiotics have evolved and diversified in nature. Insights into how bacterial polyke...

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Autores principales: Ridley, Christian P., Lee, Ho Young, Khosla, Chaitan
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2290765/
https://ncbi.nlm.nih.gov/pubmed/18250311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710107105
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