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Halothane, isoflurane and sevoflurane inhibit NADH: ubiquinone oxidoreductase (complex I) of cardiac mitochondria

We have investigated the effects of volatile anaesthetics on electron transport chain activity in the mammalian heart. Halothane, isoflurane and sevoflurane reversibly increased NADH fluorescence (autofluorescence) in intact ventricular myocytes of guinea-pig, suggesting that NADH oxidation was impa...

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Bibliografski detalji
Glavni autori: Hanley, Peter J, Ray, John, Brandt, Ulrich, Daut, Jürgen
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2002
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2290615/
https://ncbi.nlm.nih.gov/pubmed/12411515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2002.025015
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