Succinate modulation of H(2)O(2) release at NADH:ubiquinone oxidoreductase (Complex I) in brain mitochondria

Complex I (NADH:ubiquinone oxidoreductase) is responsible for most of the mitochondrial H(2)O(2) release, both during the oxidation of NAD-linked substrates and during succinate oxidation. The much faster succinate-dependent H(2)O(2) production is ascribed to Complex I, being rotenone-sensitive. In...

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Detalhes bibliográficos
Main Authors: Zoccarato, Franco, Cavallini, Lucia, Bortolami, Silvia, Alexandre, Adolfo
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1948981/
https://ncbi.nlm.nih.gov/pubmed/17477844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20070215
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