Učitavanje...

Molecular mechanism of a COOH-terminal gating determinant in the ROMK channel revealed by a Bartter's disease mutation

The ROMK subtypes of inward-rectifier K(+) channels mediate potassium secretion and regulate NaCl reabsorption in the kidney. Loss-of-function mutations in this pH-sensitive K(+) channel cause Bartter's disease, a familial salt wasting nephropathy. One disease-causing mutation truncates the ext...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Flagg, Thomas P, Yoo, Dana, Sciortino, Christopher M, Tate, Margaret, Romero, Michael F, Welling, Paul A
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2002
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2290610/
https://ncbi.nlm.nih.gov/pubmed/12381810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2002.027581
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!