The Na(+) Channel Inactivation Gate Is a Molecular Complex: A Novel Role of the COOH-terminal Domain
Electrical activity in nerve, skeletal muscle, and heart requires finely tuned activity of voltage-gated Na(+) channels that open and then enter a nonconducting inactivated state upon depolarization. Inactivation occurs when the gate, the cytoplasmic loop linking domains III and IV of the α subunit,...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2004
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2217430/ https://ncbi.nlm.nih.gov/pubmed/14744988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200308929 |
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