Molecular determinants of Au(CN)(2)(−) binding and permeability within the cystic fibrosis transmembrane conductance regulator Cl(−) channel pore

Lyotropic anions with low free energy of hydration show both high permeability and tight binding in the cystic fibrosis transmembrane conductance regulator (CFTR) Cl(−) channel pore. However, the molecular bases of anion selectivity and anion binding within the CFTR pore are not well defined and the...

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Hlavní autoři: Gong, Xiandi, Burbridge, Susan M, Cowley, Elizabeth A, Linsdell, Paul
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2002
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2290216/
https://ncbi.nlm.nih.gov/pubmed/11927667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2001.013235
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