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Membrane anchoring of the autoantigen GAD65 to microvesicles in pancreatic beta-cells by palmitoylation in the NH2-terminal domain

Pancreatic beta-cells and gamma-aminobutyric acid (GABA)-secreting neurons both express the enzyme glutamic acid decarboxylase (GAD) which is a major target of autoantibodies associated with beta-cell destruction and impairment of GABA-ergic neurotransmitter pathways. The predominant form of GAD in...

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Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 1992
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2290048/
https://ncbi.nlm.nih.gov/pubmed/1321158
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