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Palmitoylation and trafficking of GAD65 is impaired in a cellular model of Huntington disease
Huntington disease (HD) is caused by an expanded polyglutamine repeat in the huntingtin protein. GABAergic medium spiny neurons in the striatum are mostly affected in HD. However, mutant huntingtin (mhtt)-induced molecular changes in these neurons remain largely unknown. This study focuses on the ef...
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| Udgivet i: | Biochem J |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4646170/ https://ncbi.nlm.nih.gov/pubmed/22103299 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20110679 |
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